Interstate 95 (I-95) is a major north–south Interstate Highway that runs along the East Coast of the United States from Miami, Florida, north to the Canada–United States border at Houlton, Maine. In the state of Pennsylvania, it runs 51.00 miles (82.08 km) from the Delaware state line near Marcus Hook in Delaware County in the southeastern part of the state northeast to the Delaware River–Turnpike Toll Bridge at the New Jersey state line near Bristol in Bucks County, closely paralleling the New Jersey state line for its entire length through Pennsylvania.

Marcus Hook is a borough in Delaware County, Pennsylvania, United States. The population was 2,397 at the 2010 census. The current mayor is Gene Taylor. The borough calls itself "The Cornerstone of Pennsylvania". The 2005 film One Last Thing... was set and partially filmed in Marcus Hook.