Ion channel
Videos
Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore. Their functions include establishing a resting membrane potential, shaping action potentials and other
Birth of an Idea (2007) by Julian Voss-Andreae. The sculpture was commissioned by Roderick MacKinnon based on the molecule's atomic coordinates that were determined by MacKinnon's group in 2001.
Potassium channel
Videos
Potassium channels are the most widely distributed type of ion channel found in virtually all organisms. They form potassium-selective pores that span cell membranes. Potassium channels are found in m
Ion channel
…CFTRs. These channels are non-selective for small anions; however chloride is the most abundant anion, and hence they are known as chloride channels. Potassium channels Voltage-gated potassium channels e.g., Kvs, Kirs etc. Calcium-activated potassium channels e.g., BKCa or MaxiK, SK, etc. Inward-rectifier potassium…
Graphical representation of open and shut potassium channels (PDB: 1lnq and PDB: 1k4c). Two simple bacterial channels are shown to compare the "open" channel structure on the right with the "closed" structure on the left. At top is the filter (selects potassium ions), and at bottom is the gating domain (controls opening and closing of channel).