Ion channel
Videos
Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore. Their functions include establishing a resting membrane potential, shaping action potentials and other
Birth of an Idea (2007) by Julian Voss-Andreae. The sculpture was commissioned by Roderick MacKinnon based on the molecule's atomic coordinates that were determined by MacKinnon's group in 2001.
Dendrotoxin
Videos
Dendrotoxins are a class of presynaptic neurotoxins produced by mamba snakes that block particular subtypes of voltage-gated potassium channels in neurons, thereby enhancing the release of acetylcholi
3D model of α-dendrotoxin. colored in red are positively charged amino acid residues in the N-terminus and the β-turn region that are believed to be important for potassium channel binding.
Sequence alignment of dendrotoxins and BPTI. Amino acid residues with similar properties are colored accordingly.