Iowa is a landlocked state in the upper Midwestern region of the United States. It borders the Mississippi River to the east and the Missouri River and Big Sioux River to the west; Wisconsin to the northeast, Illinois to the east and southeast, Missouri to the south, Nebraska to the west, South Dakota to the northwest, and Minnesota to the north.

The Midwestern United States, also referred to as the Midwest or the American Midwest, is one of four census regions of the United States Census Bureau. It occupies the northern central part of the United States. It was officially named the North Central Region by the U.S. Census Bureau until 1984. It is between the Northeastern United States and the Western United States, with Canada to the north and the Southern United States to the south.