Iowa's 1st congressional district is a congressional district in the U.S. state of Iowa that covers its southeastern part, bordering the states of Illinois and Missouri, and the Mississippi River. The district includes the cities of Davenport, Iowa City, Burlington, and Indianola. Republican Mariannette Miller-Meeks is the current U.S. representative. With a Cook Partisan Voting Index rating of R+3, it is one of the least Republican districts in Iowa, a state with an all-Republican congressional delegation.

Mariannette Jane Miller-Meeks is an American physician and politician serving as a U.S. representative since 2021, representing Iowa's 1st congressional district. Her district, numbered as the 2nd district in her first term, includes most of Iowa's southeastern quadrant, including Davenport, Bettendorf, Burlington, and Iowa City. A member of the Republican Party, Miller-Meeks served as Iowa state senator for the 41st district from 2019 to 2021.