Iowa Wesleyan University was a private university in Mount Pleasant, Iowa, United States. It was Iowa's first co-educational institution of higher learning and the oldest of its type west of the Mississippi River. The institution was affiliated with the United Methodist Church. It closed at the end of the 2022–23 academic year due to financial challenges.

Mount Pleasant is a city in and the county seat of Henry County in the U.S. state of Iowa. The population was 9,274 in the 2020 census, an increase from 8,668 in the 2010 census. It was founded in 1835 by pioneer Presley Saunders.