Ipswich River is a small river in northeastern Massachusetts, United States. It held significant importance in early colonial migrations inland from the ocean port of Ipswich. The river provided safe harborage at offshore Plum Island Sound to early Massachusetts subsistence farmers, who were also fishermen. A part of the river forms town boundaries and divides Essex County, Massachusetts on the coast from the more inland Middlesex County. It is 35 miles (56 km) long, and its watershed is approximately 155 square miles (401 km2), with an estimated population in the area of 160,000 people.

Ipswich is a coastal town in Essex County, Massachusetts, United States. The population was 13,785 at the 2020 census. Home to Willowdale State Forest and Sandy Point State Reservation, Ipswich includes the southern part of Plum Island. A residential community with a vibrant tourism industry, the town is famous for its clams, celebrated annually at the Ipswich Chowderfest, and for Crane Beach, a barrier beach near the Crane estate. Ipswich was incorporated as a town in 1634.