Iran competed at the 2020 Summer Olympics in Tokyo. Originally scheduled to take place during the summer of 2020, the Games were postponed to 23 July to 8 August 2021, because of the COVID-19 pandemic. Since the nation's debut in 1948, Iranian athletes have attended every edition of the Summer Olympic Games, with the exception of the 1980 and 1984 which they boycotted.

The women's 100 metres event at the 2020 Summer Olympics took place on 30 and 31 July 2021 at the Japan National Stadium. 71 athletes from 55 nations competed at the event.