The Irish Red Cross Society is the National Red Cross Society for the Republic of Ireland. The society was formally established on 6 July 1939 under the Red Cross Act 1938. It is affiliated to the International Federation of Red Cross and Red Crescent Societies. The society is organised on a voluntary basis. In Ireland, its activities include mountain rescue, first aid education of the public, the provision of first aid and ambulance services at public events, as well as other community services for older people, carers, migrants and prisoners. Outside Ireland, the society provides relief and humanitarian services in response to natural disasters and in regions of conflict.

St John Ambulance Ireland (SJAI), previously known as the St John Ambulance Brigade of Ireland, is a charitable voluntary organisation in Ireland. For constitutional reasons it is not a full member association of the Venerable Order of Saint John and the international St. John Ambulance movement, but rather is classed as an "associated body". The organisation is dedicated to the teaching and practice of medical first aid. It is engaged in first aid training to the public, providing first aid and ambulance cover at public events, patient transport and community services.