The iron-responsive element-binding proteins, also known as IRE-BP, IRBP, IRP and IFR, bind to iron-responsive elements in the regulation of human iron metabolism.
Fe Regulatory Protein.pdb
Messenger RNA
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Messenger ribonucleic acid is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of synthesizing a protein.
Iron-responsive element-binding protein
…for sensing their own need for iron. In human cells, the best-characterized iron-sensing mechanism is the result of post-transcriptional regulation of mRNA (the chemical instructions derived from DNA genes to make proteins). Sequences of mRNA called iron-responsive elements (IREs) are contained within the…
Universal structure of eukaryotic mRNA, showing the structure of the 5' and 3' UTRs.
mRNA circularization and regulation
Overview of mRNA decay pathways in the different life domains.