Isetan is a Japanese department store. Based in Shinjuku, Tokyo, Isetan has branches throughout Japan and South East Asia, including in Jinan, Kuala Lumpur, Selangor, Shanghai, Singapore and Tianjin, and formerly in Bangkok, Hong Kong, Kaohsiung, London, and Vienna.

Department stores in Japan are referred to as hyakkaten or depāto (デパート), an alteration of the English term.