The Isis Highway is a state highway in southern Queensland, Australia. The highway is relatively short, and runs for 137 kilometres (85 mi) in a north-east / south-west direction between Bundaberg North and the Burnett Highway at Ban Ban Springs. The Isis Highway links the sugar producing Bundaberg and Fraser Coast regions with the cattle farming districts of the North Burnett.

Biggenden is a rural town and locality in the North Burnett Region, Queensland, Australia. In the 2021 census, the locality of Biggenden had a population of 788 people.