Iskaka is a Palestinian town in the Salfit Governorate of the State of Palestine, in the northern West Bank, 27 kilometers southwest of Nablus. According to the Palestinian Central Bureau of Statistics, it had a population of 1,198 in 2017.

Salfit governorate is one of the 16 Governorates of the State of Palestine. It is located in the northwestern West Bank, held under Israeli occupation, bordered by the governorates of Ramallah and al-Bireh to the south, Nablus to the east and Qalqilya in the north as well as, Israel to the west. Its district capital and largest city is Salfit. According to the Palestinian Central Bureau of Statistics (PCBS), the governorate had a population of 75,444 inhabitants in mid-year 2017. In the PCBS's census in 1997, which registered 46,671 residents, refugees accounted for 7.7% of the total population. There were 37,613 male residents and 36,143 females.