Isle of Hope is an unincorporated community and census-designated place (CDP) in Chatham County, Georgia, United States. It is part of the Savannah Metropolitan Statistical Area, and at the 2020 U.S. census its population was 2,357. The island is one of the most affluent communities in the state and is well known for its historic plantations and exclusive waterfront properties.

Chatham County is located in the U.S. state of Georgia, on the state's Atlantic coast. The county seat and largest city is Savannah. One of the original counties of Georgia, Chatham County was created February 5, 1777, and is named after William Pitt, 1st Earl of Chatham.