Isotopes are distinct nuclear species of the same chemical element. They have the same atomic number and position in the periodic table, but differ in nucleon numbers due to different numbers of neutrons in their nuclei. While all isotopes of a given element have similar chemical properties, they have different atomic masses and physical properties.
In the bottom right corner of J. J. Thomson's photographic plate are the separate impact marks for the two isotopes of neon: neon-20 and neon-22.
A chemical element is a chemical substance that cannot be broken down into other substances by chemical reactions. The basic particle that constitutes a chemical element is the atom. Chemical elements are identified by the number of protons in the nuclei of their atoms, known as the element's atomic number. For example, oxygen has an atomic number of 8, meaning that each oxygen atom has 8 protons in its nucleus. Two or more atoms of the same element can combine to form molecules, in contrast to chemical compounds or mixtures, which contain atoms of different elements. Atoms can be transformed into different elements in nuclear reactions, which change an atom's atomic number.
Estimated distribution of dark matter and dark energy in the universe. Only the fraction of the mass and energy in the universe labeled "atoms" is composed of chemical elements.
Portrait of Robert Boyle, c. 1740
Title page of The Sceptical Chymist, published in 1661
Portrait of Isaac Watts by John Shury, c. 1830