Israel Putnam, popularly known as "Old Put", was an American army general officer who fought with distinction at the Battle of Bunker Hill during the American Revolutionary War. He served notably as an officer with Rogers' Rangers during the French and Indian War, when he was captured by Mohawk warriors, he was saved from the ritual burning given to enemies by the intervention of a French officer with whom the Mohawk were allied. Putnam's courage and fighting spirit became known far beyond Connecticut's borders through the circulation of folk legends in the American colonies and states celebrating his exploits. Israel Putnam was born in 1718 in Salem Village, Massachusetts to Joseph and Elizabeth Putnam, a prosperous farming Puritan family, his parents had opposed the Salem witch trials in the 1690s. With his father-in-law Israel Porter, Joseph Putnam signed a petition on the behalf of the elderly Rebecca Nurse, accused of witchcraft, but the jury overturned its first verdict of innocent, convicting her and sentencing her to death.
One of her sisters was executed in the hysteria of the time. In 1740, at the age of 22, the young Putnam moved west to Mortlake, where land was cheaper and easier for young men to buy. Putnam killed a wolf in Connecticut in 1743 with the help of a group of farmers from Mortlake seeking to safeguard their sheep. After tracking the wolf to her den, they tried sending in their dogs, but all the dogs returned frightened, or in several cases, injured by the wolf, they tried smoking the wolf out, after that failed, they tried burning sulfur at the mouth of the rocky cave, all to no avail. After Putnam arrived, he tried getting his dog to enter the den, with no luck, he tried to get his servant to enter with a torch and gun to shoot the wolf. His servant refused. Putnam reportedly crawled into the den with a torch, a musket loaded with buckshot, his feet secured with rope, in order to be pulled out. While in the den, he killed the wolf. In celebration of the event, the 24-year-old Putnam was carried in a torch-lit procession through Pomfret in a celebration that lasted until about midnight.
Putnam earned the nicknames of "Wolf Putnam" and "Old Wolf Put", which stayed with him for decades afterward. A section of Mashamoquet Brook State Park in modern-day Pomfret, including the den, is named "Wolf Den"; the name "Wolf Den Road" in adjacent Brooklyn, Connecticut attests to the days of wolves. Putnam married first to Hannah Pope in 1739, the mother of his children. Two years after her death in 1765, he married Deborah Lothrop. In 1755, at the age of 37, Putnam was one of the first men in Connecticut to sign up to serve as a private in the militia in the French and Indian War. During the war, he would be successively promoted to second lieutenant, major, lieutenant colonel, colonel; as a company captain, Putnam served with Robert Rogers, who would gain fame as the commander of Rogers' Rangers, the two of them had various exploits together, in one of which Putnam saved Rogers' life. Putnam's reputation for courage was made famous by his participation in the war, it was said that "Rogers always sent, but Putnam led his men to action."In 1757, the Rangers were stationed on an island off Fort Edward.
The following February and his Rangers were still on Roger's Island when fire broke out in the row of barracks nearest the magazine. The danger of an explosion was imminent, but Putnam took a position on the roof and poured bucket after bucket of water upon the flames, only descending when the buildings fell only a few feet from the magazine. In spite of his severe wounds, he continued to fight the fire, dashing water upon the magazine until the fire was under control, he was laid up for a month due to burns and exposure. Putnam was captured on August 8, 1758, by the Kahnawake Indians from a mission settlement south of Montreal during a military campaign near Crown Point in New York, he was saved from being ritually burned alive by a rain storm and the last-minute intervention of a French officer. In 1759, Putnam led a regiment into The Valley of Death in the attack on Fort Carillon. In 1762, he survived a shipwreck during the British expedition against Cuba that led to the capture of Havana.
Major Putnam is believed to have brought back Cuban tobacco seeds to New England, which he planted in the Hartford area. This resulted in the development of the renowned Connecticut Wrapper. In 1763, during Pontiac's Rebellion, Putnam was sent with reinforcements to relieve Chief Pontiac's siege of Fort Detroit. After the war, he returned to his homestead, a remnant of which exists today as Putnam Farm in Brooklyn, Connecticut. Putnam publicly professed his Christian faith following the Seven Years' War in 1765, joined the Congregational Church in his town, he was among those. Around the time of the Stamp Act crisis in 1766, he was elected to the Connecticut General Assembly and was one of the founders of the state's chapter of the Sons of Liberty. In the fall of 1765, he threatened Thomas Fitch, the popularly elected Governor of Connecticut, over this issue, he said that Fitch's house "will be leveled with the dust in five minutes" if Fitch did not turn over the stamp tax paper to the Sons of Liberty.
By the eve of the American Revolution, Putnam had become a prosperous farmer and tavern keeper, with more than a local reputation for his previous exploits. On April 20, 1775, while plowing one of his fields with his son, he received news of the Battle of Lexington and
Alejandro "Junior" Cruz was a Puerto Rican athlete and politician, mayor of the city of Guaynabo during the 1980s and early 1990s. As a child Cruz demonstrated interest in sports softball, he progressed in that sport, becoming one of Puerto Rico's most famous softball players as a young adult. Cruz was an advocate of statehood for Puerto Rico; because of that, he became a member of the PNP party. After he finished his long and achievement-filled career as a professional softball player, he dedicated himself full-time to politics. Cruz was elected as mayor of Guaynabo in 1980. Guaynabo at the time entered a period of economic progress, alongside other cities of Puerto Rico's so-called "metropolitan area", such as Bayamon. Like his colleague Ramon Luis Rivera, Cruz became liked by many voters of Puerto Rico's three leading parties; as Mayor of Guaynabo, Cruz put emphasis on the city's sports programs, and, in 1983, the Mets Pavilion was opened. He was president of the Puerto Rican Softball Federation during much of his period as mayor of Guaynabo.
In 1989, Cruz became a founding member of a group directed towards uniting mayors of all parties in Puerto Rico, alongside Caguas mayor Angel O. Berrios, himself a member of the PPD party and two other mayors. In his latter years, Cruz suffered from cardiovascular disease, he kept serving as mayor. In 1993, Cruz suffered a fatal cerebral hemorrhage; the day after his death, his photo appeared on the covers of newspapers like El Nuevo Dia and El Vocero. Alejandro Cruz was elected to the International Softball Federation Hall of Fame in 1993, he is one of ten Puerto Ricans, including Jorge Tanco, Juan Pachot and Ivelisse Echevarria, to be inducted at that sports museum. He was honored with the naming of a high school, Alejandro Junior Cruz High in Guaynabo, after he died of a stroke. List of Puerto Ricans Puerto Rico Herald.org
Dean Ho is a Provost’s Chair Professor in the Departments of Biomedical Engineering and Pharmacology, Director of the N.1 Institute for Health, Head of the Department of Biomedical Engineering at the National University of Singapore. He was a Professor at UCLA, Associate Professor in the Departments of Biomedical Engineering and Mechanical Engineering in the Robert R. McCormick School of Engineering and Applied Science, Full Member of the Robert H. Lurie Comprehensive Cancer Center at the Feinberg School of Medicine of Northwestern University, United States. Dr. Ho's research has covered emerging areas of nanodiamond-based drug delivery. Dr. Ho and his colleagues were the first to develop nanodiamond platforms for cancer therapy and wound healing, among other areas. Dr. Ho and colleagues were the first to demonstrate the translational potential of nanodiamonds as chemotherapeutic delivery agents towards the treatment of drug-resistant cancers in vivo; this work was published as the Cover Article of the March 9 issue of the journal Science Translational Medicine.
Dr. Ho is leading 2 clinical trials to validate nanodiamond-embedded biomaterial devices for wound healing and the prevention of re-infection, he has developed nanodiamond-functionalized biomaterials for other clinically-relevant applications. Dr. Ho is known for his work in the areas of artificial intelligence and its application towards personalized and precision medicine, his team and colleagues pioneered the field of Augmented AI, which mediates model-free and mechanism-independent N-of-1 combination therapy and accelerated and globally optimized drug development. This has led to multiple clinical trials that have validated the CURATE. AI platform; this AI platform has realized best-in-class medicines for population-wide administration, as well as the unprecedented ability to actionably personalize treatment for the entire duration of care on a patient-specific basis. Dr. Ho's extensive research achievements have garnered news coverage in The Economist, Nature, CNN, NPR, as well as The Washington Post.
He was featured in the National Geographic Channel program, Known Universe. Most the Augmented AI platform was featured by FuturizeX, a partnership between the X PRIZE Foundation and UCLA. Recent clinical advances using this AI approach to enhance clinical outcomes were recognized among the finalists for the SLAS Innovation Award, selection among the SLAS Technology 10, featured at the PM3 panel at InnovFest Unbound. Dr. Ho serves as the Director of The N.1 Institute for Health, known as SINAPSE. N.1 is a clinical stage research institute that harnesses AI and Digital Medicine for novel clinical trial designs for interventional studies. Over ten first-in-human clinical studies based on N.1-developed technologies are ongoing or nearing clearance for the start of prospective clinical studies. N.1 has pioneered the development and subsequent clinical translation of platforms pertaining to N-of-1 medicine, digital therapeutics, theranostic devices, pain management, cognitive neuroengineering, novel drug development, among many others.
Dr. Ho is an elected member of the US National Academy of Inventors, he is a Fellow of the American Institute for Medical and Biological Engineering, the Society for Laboratory Automation and Screening. He was named to the 2016 Power List of The Pathologist Magazine. Dr. Ho served the Editor-in-Chief of the Journal of Laboratory Automation, now known as SLAS Technology, he served as the President of the Board of Directors of the Society for Laboratory Automation and Screening, a 20,000+ member drug development and life sciences technology organization. Dr. Ho is a recipient of the National Science Foundation CAREER Award, Wallace H. Coulter Foundation Translational Research Award, V Foundation for Cancer Research V Scholar Award, John G. Bollinger Outstanding Young Manufacturing Engineering Award of the Society of Manufacturing Engineers, UCLA School of Engineering and Applied Science Distinguished Young Alumnus Award, IADR William J. Gies Award, IADR Young Investigator Award. Robert R. McCormick School of Engineering and Applied Science Northwestern University Dance Marathon at UCLA Pi Kappa Phi