Itagüí is a city and municipality of Colombia, located in the south of the Aburrá Valley in the Antioquia Department. It is part of the Metropolitan Area of the Aburrá Valley.

Aburrá Valley, is the natural river basin of the Medellín River and one of the most populous valleys of Colombia in its Andean Region with near 4 million inhabitants in its biggest urban agglomeration: The Metropolitan Area of the Aburrá Valley. The valley is located on the Central Range, over the Antioquian Mountain just between the Magdalena and Cauca valleys from east to west. The name "Aburrá" comes from an ancient language spoken in the place by the "Aburreans" (Aburraes) before the Spaniards settled the place during the 16th century.