The Italian Renaissance was a period in Italian history covering the 15th and 16th centuries. The period is known for the initial development of the broader Renaissance culture that spread across Western Europe and marked the transition from the Middle Ages to modernity. Proponents of a "long Renaissance" argue that it started around the year 1300 and lasted until about 1600. In some fields, a Proto-Renaissance, beginning around 1250, is typically accepted. The French word renaissance means "rebirth", and defines the period as one of cultural revival and renewed interest in classical antiquity after the centuries during what Renaissance humanists labelled as the "Dark Ages". The Italian Renaissance historian Giorgio Vasari used the term rinascita ("rebirth") in his Lives of the Most Excellent Painters, Sculptors, and Architects in 1550, but the concept became widespread only in the 19th century, after the work of scholars such as Jules Michelet and Jacob Burckhardt.

The European country of Italy has been inhabited by humans since at least 850,000 years ago. Since classical antiquity, ancient Etruscans, various Italic peoples, Celts, Magna Graecia colonists, and other ancient peoples have inhabited the Italian Peninsula.