Regina Margherita was the lead ship of her class of pre-dreadnought battleships built for the Italian Regia Marina between 1898 and 1904. She had one sister ship, Benedetto Brin. Regina Margherita saw action in the Italo-Turkish War of 1911–1912. By the outbreak of World War I in 1914, the battleship had been reduced to a training ship. She struck two naval mines on the night of 11–12 December 1916 while steaming off Valona. She sank with heavy loss of life: 675 men were killed, and only 270 survived.

The Regina Margherita class was a class of two battleships built for the Italian Regia Marina between 1898 and 1905. The class comprised two ships: Regina Margherita and Benedetto Brin. The ships were designed by the latter's namesake, Benedetto Brin, who died before the ships were completed. They were armed with a main battery of four 12 in (305 mm) guns and could steam at a speed of 20 knots.