Itoigawa is a city located in Niigata Prefecture, Japan. As of 31 January 2020, the city had an estimated population of 41,333, and a population density of 55 persons per km2. The total area of the city is 746.24 square kilometres (288.12 sq mi).

The Echigo TOKImeki Railway Company (ETR) is a Japanese third-sector railway operating company established in 2010 to operate passenger railway services on the sections of the JR East Shinetsu Main Line and JR West Hokuriku Main Line within Niigata Prefecture when they were separated from the respective JR Group operators in March 2015, coinciding with the opening of the Hokuriku Shinkansen extension from Nagano to Kanazawa. The main shareholders of the company are Niigata Prefecture, the city of Joetsu, the city of Itoigawa, and the city of Myoko.