Iztapalapa is a borough in Mexico City, located on the east side of the entity. The borough is named after and centered on the formerly independent municipality of Iztapalapa, which is officially called Iztapalapa de Cuitláhuac for disambiguation purposes. The rest is made up of a number of other communities which are governed by the city of Iztapalapa.

Mexico City is the capital and largest city of Mexico, and the most populous city in North America. Mexico City is one of the most important cultural and financial centers in the world. It is located in the Valley of Mexico within the high Mexican central plateau, at an altitude of 2,240 meters (7,350 ft). The city has 16 boroughs or demarcaciones territoriales, which are in turn divided into neighborhoods or colonias.