Jackson Square station is a Massachusetts Bay Transportation Authority (MBTA) Orange Line rapid transit station located on Centre Street near Columbus Avenue in the Jamaica Plain neighborhood of Boston, Massachusetts. The station opened in 1987 as part of the Southwest Corridor project. It is served by MBTA bus routes 14, 22, 29, 41, and 44, which operate into an off-street busway located adjacent to the station.

The Orange Line is a rapid transit line operated by the Massachusetts Bay Transportation Authority (MBTA) as part of the MBTA subway system. The line runs south on the surface from Oak Grove station in Malden, Massachusetts through Malden and Medford, paralleling the Haverhill Line, then crosses the Mystic River on a bridge into Somerville, then into Charlestown. It passes under the Charles River and runs through Downtown Boston in the Washington Street Tunnel. The line returns to the surface in the South End, then follows the Southwest Corridor southwest in a cut through Roxbury and Jamaica Plain to Forest Hills station.