Jackson, MS Metropolitan Statistical Area is a metropolitan statistical area (MSA) in the central region of the U.S. state of Mississippi that covers seven counties: Copiah, Hinds, Holmes, Madison, Rankin, Simpson, and Yazoo. As of the 2010 census, the Jackson MSA had a population of 586,320. According to 2019 estimates, the population has slightly increased to 594,806. Jackson is the principal city of the MSA.

Simpson County is a county located in the U.S. state of Mississippi. Its western border is formed by the Pearl River, an important transportation route in the 19th century. As of the 2020 census, the population was 25,949. The county seat is Mendenhall. The county is named for Josiah Simpson (1787-1817), a territorial judge who also served as a delegate to Mississippi's Constitutional Convention.