Jacob Dolson Cox, Jr., was a statesman, lawyer, Union Army general during the American Civil War, Republican politician from Ohio, Liberal Republican Party founder, educator, author, and recognized microbiologist. He served as president of the University of Cincinnati, the 28th governor of Ohio and as United States Secretary of the Interior. As Governor of Ohio, Cox sided for a time with President Andrew Johnson's Reconstruction plan and was against African American suffrage in the South, though he supported it in Ohio. However, Cox increasingly expressed racist and segregationist viewpoints, advocating a separate colony for blacks to "work out their own salvation." Seeing himself caught between Johnson and the Radical Republicans, Cox decided not to run for reelection. He stayed out of politics for a year, though both Sherman and Grant advocated that Cox replace Stanton as Secretary of War as a means of stemming the demands for Johnson's impeachment. But Johnson declined. When Ulysses S. Grant became president, he nominated Cox Secretary of Interior, and Cox immediately accepted.

The Liberal Republican Party was an American political party that was organized in May 1872 to oppose the reelection of President Ulysses S. Grant and his Radical Republican supporters in the presidential election of 1872. The party emerged in Missouri under the leadership of Senator Carl Schurz and soon attracted other opponents of Grant; Liberal Republicans decried the scandals of the Grant administration and sought civil service reform. The party opposed Grant's Reconstruction policies, particularly the Enforcement Acts that destroyed the Ku Klux Klan. It lost in a landslide, and disappeared from the national stage after the 1872 election.