The James A. Burden House is a mansion at 7 East 91st Street in the Carnegie Hill section of the Upper East Side of Manhattan in New York City. The five-story mansion was designed by architects Warren and Wetmore in the Beaux-Arts style. It was completed in 1905 as the residence of iron entrepreneur James A. Burden Jr. and his wife Florence Sloane Burden. The Convent of the Sacred Heart, a private school, owns the Burden House along with the adjacent Otto H. Kahn House, which is internally connected. The mansion is a New York City designated landmark and, along with the Kahn House, is listed on the National Register of Historic Places.

Convent of the Sacred Heart is an American independent Roman Catholic all-girls' school in the Manhattan borough of New York City.