James Franck was a German physicist who won the 1925 Nobel Prize for Physics with Gustav Hertz "for their discovery of the laws governing the impact of an electron upon an atom". He completed his doctorate in 1906 and his habilitation in 1911 at the Frederick William University in Berlin, where he lectured and taught until 1918, having reached the position of professor extraordinarius. He served as a volunteer in the German Army during World War I. He was seriously injured in 1917 in a gas attack and was awarded the Iron Cross 1st Class.

The Metallurgical Laboratory was a scientific laboratory at the University of Chicago that was established in February 1942 to study and use the newly discovered chemical element plutonium. It researched plutonium's chemistry and metallurgy, designed the world's first nuclear reactors to produce it, and developed chemical processes to separate it from other elements. In August 1942 the lab's chemical section was the first to chemically separate a weighable sample of plutonium, and on 2 December 1942, the Met Lab produced the first controlled nuclear chain reaction, in the reactor Chicago Pile-1, which was constructed under the stands of the university's old football stadium, Stagg Field.