James Hervey Otey, Christian educator, author, and the first Episcopal Bishop of Tennessee, having established the Anglican church in the state, including its first parish churches and what became the University of the South.

The Mathews family is an American political family originally descended from Samuel Mathews (d.1657) [and later American pioneer John Mathews] and Ann Archer, originating in colonial Virginia and active in Virginia and the American South in the 17th–20th centuries.