James Howard Meredith is an American civil rights activist, writer, political adviser, and United States Air Force veteran who became, in 1962, the first African-American student admitted to the racially segregated University of Mississippi after the intervention of the federal government. Inspired by President John F. Kennedy's inaugural address, Meredith decided to exercise his constitutional rights and apply to the University of Mississippi. His goal was to put pressure on the Kennedy administration to enforce civil rights for African Americans. The admission of Meredith ignited the Ole Miss riot of 1962 where Meredith's life was threatened and 31,000 American servicemen were required to quell the violence – the largest ever invocation of the Insurrection Act of 1807.

The University of Mississippi is a public research university that is located adjacent to Oxford, Mississippi, and has a medical center in Jackson. It is Mississippi's oldest public university and it is the second largest by enrollment.