The James River Bridge (JRB) is a four-lane divided highway lift bridge across the James River in the Commonwealth of Virginia. Owned and operated by the Virginia Department of Transportation, it carries U.S. Route 17 (US 17), US 258, and State Route 32 across the river near its mouth at Hampton Roads. The bridge connects Newport News on the Virginia Peninsula with Isle of Wight County in the South Hampton Roads region, and is the easternmost such crossing without a tunnel component.

The James River is a river in Virginia that begins in the Appalachian Mountains and flows from the confluence of the Cowpasture and Jackson Rivers in Botetourt County 348 miles (560 km) to the Chesapeake Bay. The river length extends to 444 miles (715 km) if the Jackson River is included, the longer of its two headwaters. It is the longest river in Virginia. Jamestown and Williamsburg, Virginia's first colonial capitals, and Richmond, Virginia's current capital, lie on the James River.