The James Whitcomb Riley was a passenger train that operated between Chicago, Illinois, and Cincinnati, Ohio, via Indianapolis, Indiana. Originally operated by the New York Central Railroad, it was taken over by Amtrak in 1971. Under Amtrak, it merged with the Chesapeake & Ohio Railway's George Washington to become a Chicago-Washington/Newport News train. In 1977, it was renamed the Cardinal, which remains in operation.

The George Washington was a named passenger train of the Chesapeake and Ohio Railway running between Cincinnati, Ohio and Washington, D.C. that operated from 1932, the 200th anniversary of the birth of George Washington, to 1974. A section divided from the main train at Gordonsville, Virginia and operated through Richmond to Phoebus, Virginia. From the west, a section originated in Louisville and joined at Ashland.