James Evan Wilson, M.D., is a fictional character on the Fox medical drama House. He is played by Robert Sean Leonard. The character first appears in the show's pilot episode when he introduces a medical case to the protagonist, Dr. Gregory House. Wilson is Dr. House's only true friend; he frequently provides him with consultations and aid. Wilson is the head of the Department of Oncology at Princeton-Plainsboro Teaching Hospital.

Robert Lawrence Leonard, known by his stage name Robert Sean Leonard, is an American actor. He is known for playing Dr. James Wilson in the television series House (2004–2012) and Neil Perry in the 1989 film Dead Poets Society.