James Zadroga was a New York City Police Department (NYPD) officer who died of a respiratory disease that has been attributed to his participation in rescue and recovery operations in the rubble of the World Trade Center following the September 11 attacks. Zadroga was the first NYPD officer whose death was attributed to exposure to his contact with toxic chemicals at the attack site.

The James Zadroga 9/11 Health and Compensation Act of 2010 is a U.S. law to provide health monitoring and aid to the first responders, volunteers, and survivors of the September 11 attacks. It is named after James Zadroga, a New York Police Department officer whose death was linked to exposures from the World Trade Center disaster. The law funds and establishes a health program to provide medical treatment for responders and survivors who experienced or may experience health complications related to the 9/11 terrorist attacks.