Jamestown station is a historic train station located at Jamestown in Chautauqua County, New York. Although no longer an active railroad station due to a lack of passenger service in the area after a restoration done in 2011 the building currently serves as a bus transportation center and community space for Jamestown. The first train arrived at Jamestown on August 25, 1860 as part of the Atlantic and Great Western Railroad.

Jamestown is a city in southern Chautauqua County, New York, United States. The population was 28,712 at the 2020 census. Situated between Lake Erie to the north and the Allegheny National Forest to the south, Jamestown is the largest city in the county. Nearby Chautauqua Lake is a freshwater resource used by fishermen, boaters, and naturalists.