Jean de Lorraine was the third son of the ruling Duke of Lorraine, and a French cardinal, who was archbishop of Reims (1532–1538), Lyon (1537–1539), and Narbonne (1524–1550), bishop of Metz, and Administrator of the dioceses of Toul, Verdun, Thérouanne, Luçon, Albi, Valence, Nantes and Agen (1538–1550). He was a personal friend, companion, and advisor of King Francis I of France. Jean de Lorraine was the richest prelate in the reign of Francis I, as well as the most flagrant pluralist. He is one of several cardinals known as the Cardinal de Lorraine.

The Diocese of Toul was a Roman Catholic diocese seated at Toul in present-day France. It existed from 365 until 1802. From 1048 until 1552, it was also a state of the Holy Roman Empire.