Jeanette Jo Epps is an American aerospace engineer and NASA astronaut. Epps received both her M. S. and Ph.D. degrees in aerospace engineering from the University of Maryland, where she was part of the rotor-craft research group and was a NASA GSRP Fellow. She was chosen for the 20th class of NASA astronauts in 2009, graduating in 2011. Epps currently serves as a member of the ISS Operations Branch and has completed analog astronaut missions, including NEEMO 18 and CAVES 19. She is the second woman and first African-American woman to have participated in CAVES. She is currently in space for a long duration mission on the ISS, after launch in 4 March 2024, as part of the SpaceX Crew-8 crew.

NASA Extreme Environment Mission Operations, or NEEMO, is a NASA analog mission that sends groups of astronauts, engineers and scientists to live in the Aquarius underwater laboratory, the world's only undersea research station, for up to three weeks at a time in preparation for future space exploration.