Jeff Caxide is an American bassist, best known for his time with post-metal band Isis, of which he was a founding member and present until its dissolution in 2010. He was also a founding member of Red Sparowes, but left after the release of their first full-length. He also contributed to side-project Spylacopa. Prior to his time in Isis, he was a touring member of the Boston metalcore band 454 Big Block. He also helped found Connecticut-based metalcore band Cable, for whom he played bass. His stay with the band as a musician was brief, but he did return in order to produce 1999's Gutter Queen.

Isis was an American post-metal band formed in Boston, Massachusetts in 1997 by guitarist and vocalist Aaron Turner, bassist Jeff Caxide, vocalist and electronic instrumentalist Chris Mereschuk and drummer Aaron Harris. After a demo and the EP Mosquito Control were recorded by the original lineup, Mereschuk was replaced by Jay Randall in 1999, who joined the group alongside guitarist Michael Gallagher. Jay Randall would later be replaced by guitarist and keyboardist Bryant Clifford Meyer after the recording of Red Sea. With roots in hardcore punk and doom metal, the band borrowed from and helped to evolve the post-metal sound pioneered by bands such as Neurosis and Godflesh, characterized by lengthy songs focusing on repetition and evolution of structure. Isis disbanded in June 2010, just before the release of a split EP with the Melvins, reforming only once in 2018 as Celestial for a one-off show to pay tribute to Caleb Scofield.