Jeffrey Scot Tweedy is an American musician, songwriter, author, and record producer best known as the singer and guitarist of the band Wilco. Tweedy, originally from Belleville, Illinois, began his music career in high school with his band The Plebes along with Jay Farrar, also in the band. It became the alternative country band Uncle Tupelo.

Wilco is an American rock band based in Chicago. The band was formed in 1994 by the remaining members of alternative country group Uncle Tupelo after singer Jay Farrar's departure. Wilco's lineup changed frequently during its first decade, with only singer Jeff Tweedy and bassist John Stirratt remaining from the original incarnation. Since early 2004 the lineup has been unchanged, consisting of Tweedy, Stirratt, guitarist Nels Cline, multi-instrumentalist Pat Sansone, keyboard player Mikael Jorgensen, and drummer Glenn Kotche. Wilco has released thirteen studio albums, a live double album, and four collaborations: three with Billy Bragg and one with the Minus 5.