Jefferson Park is a neighborhood in the South Los Angeles region of the City of Los Angeles, California. There are fourteen Los Angeles Historic-Cultural Monuments in the neighborhood, and in 1987, the 1923 Spanish Colonial Revival Jefferson Branch Library was added to the National Register of Historic Places. A portion of the neighborhood is a designated Historic Preservation Overlay Zone (HPOZ).

South Los Angeles, also known as South Central Los Angeles or simply South Central, is a region in southwestern Los Angeles County, California, lying mostly within the city limits of Los Angeles, south of downtown. It is "defined on Los Angeles city maps as a 16-square-mile (41 km2) rectangle with two prongs at the south end.” In 2003, the Los Angeles City Council renamed this area "South Los Angeles".