Jerusalem's Lot, Maine is a fictional town and a part of writer Stephen King's fictional Maine topography. 'Salem's Lot has served as the setting for a number of his novels, novellas, and short stories. It first appeared in King's 1975 novel 'Salem's Lot, and has reappeared as late as his 2019 novel The Institute. The town is described as being located in Cumberland County, between the towns of Falmouth, Windham, and Cumberland, near the southern part of the state about 10 miles north of Portland. A map on King's official website, though, places 'Salem's Lot considerably further north, approximately in Northwest Piscataquis.

'Salem's Lot is a 1975 horror novel by American author Stephen King. It was his second published novel. The story involves a writer named Ben Mears who returns to the town of Jerusalem's Lot in Maine, where he lived from the age of five through nine, only to discover that the residents are becoming vampires. The town is revisited in the short stories "Jerusalem's Lot" and "One for the Road", both from King's story collection Night Shift (1978). The novel was nominated for the World Fantasy Award in 1976 and the Locus Award for the All-Time Best Fantasy Novel in 1987.