The Jiajing wokou raids caused extensive damage to the coast of China in the 16th century, during the reign of the Jiajing Emperor in the Ming dynasty. The term "wokou" originally referred to Japanese pirates who crossed the sea and raided Korea and China; however, by the mid-Ming, the wokou consisted of multinational crewmen that included the Japanese and the Portuguese, but a great majority of them were Chinese instead. Mid-Ming wokou activity began to pose a serious problem in the 1540s, reached its peak in 1555, and subsided by 1567, with the extent of the destruction spreading across the coastal regions of Jiangnan, Zhejiang, Fujian, and Guangdong.

Wokou, which translates to "Japanese pirates", were pirates who raided the coastlines of China and Korea from the 13th century to the 17th century. The wokou were made of various ethnicities of East Asian ancestry, which varied over time and raided the mainland from islands in the Sea of Japan and East China Sea. Wokou activity in Korea declined after the Treaty of Gyehae in 1443 but continued in Ming China and peaked during the Jiajing wokou raids in the mid-16th century. Chinese reprisals and strong clamp-downs on pirates by Japanese authorities saw the wokou disappear by the 17th century.