Jim Wells County is a county in the U.S. state of Texas. As of the 2020 census, its population was 38,891. The county was founded in 1911 and is named for James B. Wells Jr. (1850–1923), for three decades a judge and Democratic Party political boss in South Texas.

South Texas is a region of the U.S. state of Texas that lies roughly south of—and includes—San Antonio. The southern and western boundary is the Rio Grande, and to the east it is the Gulf of Mexico. The population of this region is about 4.96 million according to the 2017 census estimates. The southern portion of this region is often referred to as the Rio Grande Valley. The eastern portion along the Gulf of Mexico is also referred to as the Coastal Bend.