James McNulty is a fictional character and the protagonist of the HBO drama The Wire, played by Dominic West.

Avon Randolph Barksdale is a fictional character in the American television series The Wire, played by Wood Harris. Barksdale is one of the most powerful drug dealers in Baltimore, Maryland, and runs the Barksdale Organization. Stringer Bell, his second in command, insulates Barksdale from law enforcement and potential enemies. Working for Barksdale and Bell is a large organization of drug dealers and enforcers.