Johann Christoph Pepusch, also known as John Christopher Pepusch and Dr Pepusch, was a German-born composer who spent most of his working life in England. He was born in Berlin, son of a vicar, and was married to Margherita de l'Epine who also performed in some of his theatrical productions.

Margherita de L'Épine was an Italian soprano of the Baroque era. She was among the most popular and successful of London's female singers in the years just before and after Italian opera became introduced to the city. Today, she is best remembered for her performances in the operas of George Frideric Handel, and her longstanding association with the composer Johann Pepusch, whom it seems she married around 1718.