Sir John Charles Molteno was a politician and businessman who served as the first Prime Minister of the Cape Colony from 1872 to 1878.

The Cape Colony, also known as the Cape of Good Hope, was a British colony in present-day South Africa named after the Cape of Good Hope. It existed from 1795 to 1802, and again from 1806 to 1910, when it united with three other colonies to form the Union of South Africa, then became the Cape Province, which existed even after 1961, when South Africa had become a republic, albeit, temporarily outside the Commonwealth of Nations (1961–94).