John Edward Sununu is an American politician who served as a member of the U.S. House of Representatives from 1997 to 2003 and the U.S. Senate representing New Hampshire from 2003 to 2009. Sununu was the youngest member of the Senate for his entire six-year term. He also remains the only Salvadoran American ever elected to the U.S. Congress.

The United States Senate election in New Hampshire was held on November 4, 2008. Incumbent Republican U.S. Senator John E. Sununu ran for re-election to a second term, but was defeated by Democrat Jeanne Shaheen in a rematch of the 2002 election. Shaheen's win marked the first time since 1972 that Democrats won this seat, and made her the first Democratic Senator elected from New Hampshire since John A. Durkin's victory in 1975.