John Mayhew was an English musician, best known for his brief tenure as the drummer of the progressive rock band Genesis. He replaced the band's previous drummer, John Silver, in August 1969, and was himself replaced in August 1970 by Phil Collins. Mayhew appears on the album Trespass, as well as the Genesis Archive 1967-75 and Genesis 1970–1975 box sets.

Genesis were an English rock band formed at Charterhouse School, Godalming, Surrey, in 1967. The band's longest-existing and most commercially successful line-up consisted of keyboardist Tony Banks, bassist/guitarist Mike Rutherford and drummer/singer Phil Collins. In the 1970s, during which the band also included singer Peter Gabriel and guitarist Steve Hackett, Genesis were among the pioneers of progressive rock.