John Theophilus Desaguliers FRS was a British natural philosopher, clergyman, engineer and freemason who was elected to the Royal Society in 1714 as experimental assistant to Isaac Newton. He had studied at Oxford and later popularized Newtonian theories and their practical applications in public lectures. Desaguliers's most important patron was James Brydges, 1st Duke of Chandos. As a Freemason, Desaguliers was instrumental in the success of the first Grand Lodge in London in the early 1720s and served as its third Grand Master.

The organisation now known as the Premier Grand Lodge of England was founded on 24 June 1717 as the Grand Lodge of London and Westminster. Originally concerned with the practice of Freemasonry in London and Westminster, it soon became known as the Grand Lodge of England. Because it was the first Masonic Grand Lodge to be created, modern convention now calls it the Premier Grand Lodge of England in order to distinguish it from the Most Ancient and Honourable Society of Free and Accepted Masons according to the Old Constitutions, usually referred to as the Ancient Grand Lodge of England, and the Grand Lodge of All England Meeting at York. It existed until 1813, when it united with the Ancient Grand Lodge of England to create the United Grand Lodge of England.