John Baptist Tuohill Murphy, C.S.Sp. was an Irish Roman Catholic priest in the Congregation of the Holy Ghost, who served from 1886 to 1899 as the president of the Pittsburgh Catholic College, which was later renamed Duquesne University in 1911 when it gained university status. Later, Murphy was consecrated as a bishop and administered the Roman Catholic Diocese of Port-Louis in Mauritius until his death.

Martin A. Hehir C.S.Sp. was a Roman Catholic priest and the fourth president of Pittsburgh Catholic College. Hehir served as president of the university from 1899 until 1930. In Hehir's thirty-one years of presidency, the small college grew to become a university and the seventh largest Catholic school in the United States. After his retirement, Hehir served as Superior of the Holy Ghost Missionary College near Philadelphia, and then as the Superior of the Spiritan Fathers at Ferndale Seminary in Norwalk, Connecticut, until his death.