Johnny Zacchara is a fictional character on the ABC soap opera General Hospital and the contract role was portrayed by Brandon Barash from September 18, 2007, until May 3, 2013. He returned on December 5, 2014. He is the son of Claudia Zacchara and Gino Soleito. Until its reveal in 2012, he was believed to be the son of mobster Anthony Zacchara, who turned out to be his biological grandfather.

General Hospital is an American daytime television soap opera. It is listed in Guinness World Records as the longest-running American soap opera in production, and the second in American history after Guiding Light. Concurrently, it is the world's third longest-running scripted drama series in production after British serials The Archers and Coronation Street, as well as the world's second-longest-running televised soap opera still in production. General Hospital premiered on the ABC television network on April 1, 1963. General Hospital is the longest-running serial produced in Hollywood, and the longest-running entertainment program in ABC television history. It holds the record for most Daytime Emmy Awards for Daytime Emmy Award for Outstanding Drama Series, with 14 wins.