Jonesboro is a town in, and the parish seat of, Jackson Parish in the northern portion of the U.S. state of Louisiana. The population was 4,106 in 2020.

Jackson Parish is a parish in the northern part of the U.S. state of Louisiana. As of the 2020 census, the population was 15,031. The parish seat is Jonesboro. The parish was formed in 1845 from parts of Claiborne, Ouachita, and Union Parishes. In the twentieth century, this part of the state had several small industrial mill towns, such as Jonesboro.