José Miguel Carrera Verdugo was a Chilean general, formerly Spanish military, member of the prominent Carrera family, and considered one of the founders of independent Chile. Carrera was the most important leader of the Chilean War of Independence during the period of the Patria Vieja. After the Spanish "Reconquista de Chile" ("Reconquest"), he continued campaigning from exile after defeat. His opposition to the leaders of independent Argentina and Chile, San Martín and O'Higgins respectively, made him live in exile in Montevideo. From Montevideo Carrera traveled to Argentina where he joined the struggle against the unitarians. Carreras' small army was eventually left isolated in the Province of Buenos Aires from the other federalist forces. In this difficult situation Carrera decided to cross to native-controlled lands all the way to Chile to once and for all overthrow Chilean Supreme Director O'Higgins. His passage to Chile, which was his ultimate goal, was opposed by Argentine politicians and he engaged together with indigenous tribes, among them the Ranquel, in a campaign against the southern provinces of Argentina. After the downfall of Carrera's ally, the Republic of Entre Ríos, and several victories against the United Provinces of the Río de la Plata, Carrera's men were finally defeated by numerically superior forces near Mendoza. Carrera was then betrayed by one of his Argentine helpers, leading to his capture and execution in that city.

José Francisco de San Martín y Matorras, nicknamed "the Liberator of Argentina, Chile and Peru", was an Argentine general and the primary leader of the southern and central parts of South America's successful struggle for independence from the Spanish Empire who served as the Protector of Peru. Born in Yapeyú, Corrientes, in modern-day Argentina, he left the Viceroyalty of the Río de la Plata at the early age of seven to study in Málaga, Spain.